Sensing Nanopores on Yeast Cells via Pulsed Electric Fields

Electroporation is a physical phenomenon that involves the structural rearrangement and formation of nanopores as a result of a pulsed electric field application. In COMSOL, a computational model was developed to investigate the dynamic behaviour of pore expansion in biological cells with a cell wall during electroporation. This model examines the dynamics of nanopores in yeast cells. The results indicate that a field strength of 400 kV/m generates a voltage across the cell wall. Additionally, longer pulse widths lead to the formation of larger nanopores in the pole region of the cell.